Conférences Centre de Recherche Cerveau & Cognition - UMR5549


Université Paul Sabatier


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23 January 2017

What are the brain regions that process visual information when we walk within our environment?

What are the brain regions that process visual information when we walk within our environment? Are they identical in human and non-human primates, species that are very close by on the evolutionary tree? In order to answer these questions, researchers from the ECO-3D team used a neuroimaging technique based on fMRI recordings at high field (3T) in awake behaving macaque. This state-of-art approach was developed in parallel in human and monkey over the last 5 years within the MRI platform of the ‘Institut des Sciences du Cerveau de Toulouse’ on the site of the Purpan hospital. This platform is one of the first in France that was specifically designed for studies in both human and macaque. Numerous tests were necessary for the establishment of fMRI sequences, the development of specific coils but also for the processing of the data and the conditioning of the animals. The results, published in Cerebral Cortex, revealed that despite some differences, the cortical networks activated during locomotion in macaques are very close to those obtained in humans using the same experimental approach. They allow a better understanding of the homologies between the two species and open new perspectives on our current knowledge of brain function evolution in primate.

19 July 2016

Cécile JUAN : Prix du Poster au Forum international de la recherche en multi sensorialité

Cécile JUAN, is honored by the prize of the outstanding Award Certificate of the organizing comitte of the 17th international multisensory research forum for her work on Auditory-visual integration in the posterior cingulate cortex of the macaque monkeys. Son poster a été présenté au 17ème Forum international sur la recherche en multisensorialité (IMRF) qui s’est déroulé à Suzhou en chine du 15 au 18 juin 2016. This study shows first neuronal evidence of the visuo-auditory integration in the PCC of awake monkeys. These stimuli could be treated later as spatial markers to avoid or direct to when the animal explores its environment.

9 March 2016

Médaille d’honneur du CNRS

On Tuesday, March 8th, 2016, Michèle FABRE-THORPE and Catherine MARLOT saw awarding the medal of honor of the CNRS(NATIONAL CENTER FOR SCIENTIFIC RESEARCH) for the quality of services provided.

Médaille_Michèle Médaille_Catherine

The CNRS(NATIONAL CENTER FOR SCIENTIFIC RESEARCH) wishes to honor all those who contributed to its brilliance, either directly by their scientific activity, or more indirectly, by allowing by their daily activity that the research can be made in the best possible conditions. A medal of honor of the CNRS was created to honor, at the time of their retirement, the staffs researchers, engineers, technicians and administration staff for their participation in the research activity during numerous years.

17 December 2015


TNAP is a ubiquitous enzyme with a wide spectrum of substrates and cellular functions. Lack of TNAP activity is a lethal condition. Our finding of a highly specific regional, laminar and subcellular localization of TNAP in the cerebral cortex indicates that in addition to metabolic and skeletal functions TNAP also plays a role in regulating cerebral functions most probably cognition. In fact TNAP disturbance could result in complex diseases such as epilepsy, developmental retardation and Alzheimer disease. The book, a systematic collection of chapters written by experts from different fields, is the first survey about our present knowledge in regard to the neural functions of TNAP. As such this book is a good source of information for clinicians and researchers and it also paves the way to future research directions in the field.

17 December 2015

Attention searches nonuniformly in space and in time

Difficult search tasks are known to involve attentional resources, but the spatiotemporal behavior of attention remains unknown. Are multiple search targets processed in sequence or in parallel? We developed an innovative methodology to solve this notoriously difficult problem. Observers performed a difficult search task during which two probes were flashed at varying delays. Performance in reporting probes at each location was considered a measure of attentional deployment. By solving a second-degree equation, we determined the probability of probe report at the most and least attended probe locations on each trial. Because these values differed significantly, we conclude that attention was focused on one stimulus or subgroup of stimuli at a time, and not divided uniformly among all search stimuli. Furthermore, this deployment was modulated periodically over time at ∼7 Hz. These results provide evidence for a nonuniform spatiotemporal deployment of attention during difficult search. .

Figure : Les performances d’identification de deux stimuli-sondes, flashés à des délais variables au cours d’une recherche visuelle, ont permis la résolution d’une équation du second degré déterminant la probabilité d’identifier correctement ces stimuli à la position la plus attendue (P1) et la moins attendue (P2) de l’espace visuel. Ces valeurs différaient significativement (différence supérieure à zéro) et variaient au cours du temps. Au cours de la recherche visuelle, l’attention se focalisait sur un stimulus (ou groupe de stimuli) à la fois, et n’était pas divisée uniformément sur tous les stimuli.

© Laura Dugué. Douglas McLelland. Mathilde Lajous. Rufin VanRullen

To be noted

Semaine du Cerveau 2017

La semaine du Cerveau 2017 se déroulera du 13 au 18 mars. Programme

Conférences et séminaires

Conférence CerCo
Martin Szinte
Ludwig-Maximilians-Universität Münich
mardi 09 mai 2017 11h
Salle de conférence (Pavillon Baudot), Hôpital Purpan
Perceiving a stable world through the predictive allocation of attention

Conférence CerCo
Heiko Hecht
Johannes Gutenberg Universität, Mainz, Germany
jeudi 11 mai 2017 14
Salle de conférence (Pavillon Baudot), Hôpital Purpan
2D - 3D - fake 3D - and genuine reality


L’association InCOGnu organise régulièrement des soirées débats et ateliers autour des Sciences Cognitives. More...